Reactome | USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10885091] cysteine-type deubiquitinase activity of USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-DME-6781764] USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10885082
displayName	USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
hasComponent	[GenomeEncodedEntity:R-DME-2173138] Ghost homologue of USP15 [cytosol] [DefinedSet:R-DME-6782776] Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Homo sapiens
maxDepth	4
name	USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-6782777
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DME-6781764] USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1
(physicalEntity)	[CatalystActivity:10885091] cysteine-type deubiquitinase activity of USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
(inferredTo)	[Complex:R-HSA-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]

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