Reactome | DNA polymerases delta, epsilon or kappa bind the TC-NER site

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DNA polymerases delta, epsilon or kappa bind the TC-NER site Show undefined attributes

authored	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6782207] Orlic-Milacic, Marija, 2015-06-05
dbId	6782211
displayName	DNA polymerases delta, epsilon or kappa bind the TC-NER site
edited	[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015-06-16
eventOf	[Pathway:R-HSA-6782135] Dual incision in TC-NER - Homo sapiens
followingEvent	[Reaction:R-HSA-6782224] 3' incision by ERCC5 (XPG) in TC-NER - Homo sapiens
input	[DefinedSet:R-HSA-6790532] PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] [DefinedSet:R-HSA-6790535] POLD,POLE,POLK [nucleoplasm] [Complex:R-HSA-68436] RFC Heteropentamer [nucleoplasm] [Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5690036] Coordination of dual incision and repair synthesis in human nucleotide excision repair [LiteratureReference:5690466] Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	DNA polymerases delta, epsilon or kappa bind the TC-NER site
orthologousEvent	[Reaction:R-MMU-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Mus musculus [Reaction:R-PFA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Plasmodium falciparum [Reaction:R-SCE-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Saccharomyces cerevisiae [Reaction:R-SPO-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Schizosaccharomyces pombe [Reaction:R-DDI-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Dictyostelium discoideum [Reaction:R-CEL-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Caenorhabditis elegans [Reaction:R-DME-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Drosophila melanogaster [Reaction:R-GGA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Gallus gallus [Reaction:R-DRE-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Danio rerio [Reaction:R-SSC-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Sus scrofa [Reaction:R-BTA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Bos taurus [Reaction:R-CFA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Canis familiaris [Reaction:R-RNO-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Rattus norvegicus
output	[Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6790576] Fousteri, Maria, 2015-08-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6782211
summation	[Summation:6782217] The DNA repair synthesis complex, consisting of PCNA, RFC, R...

Referrals

(hasEvent)	[Pathway:R-HSA-6782135] Dual incision in TC-NER
(precedingEvent)	[Reaction:R-HSA-6782224] 3' incision by ERCC5 (XPG) in TC-NER

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