Reactome | RNA Polymerase II Pre-transcription Events

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RNA Polymerase II Pre-transcription Events Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:674696] Gillespie, ME, 2010-05-05
dbId	674695
deleted	[Deleted:8985725] Deletion of instance: 112387 [Deleted:2076699] Deletion of instance: 112386
displayName	RNA Polymerase II Pre-transcription Events
eventOf	[Pathway:R-HSA-73857] RNA Polymerase II Transcription - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond - Homo sapiens [Reaction:R-HSA-75891] Abortive Initiation After Second Transition - Homo sapiens [Reaction:R-HSA-75856] Abortive Initiation Before Second Transition - Homo sapiens [Reaction:R-HSA-112434] Formation of DSIF complex - Homo sapiens [Reaction:R-HSA-112435] Formation of Elongin BC complex - Homo sapiens [Reaction:R-HSA-112429] Formation of FACT complex - Homo sapiens [Reaction:R-HSA-112437] Formation of NELF complex - Homo sapiens [Reaction:R-HSA-112430] Formation of P-TEFb complex - Homo sapiens [Reaction:R-HSA-112436] Formation of Elongin complex - Homo sapiens [Reaction:R-HSA-112392] Resumption of elongation after recovery from pausing - Homo sapiens [Reaction:R-HSA-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing - Homo sapiens [Reaction:R-HSA-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Homo sapiens [Reaction:R-HSA-113413] TFIIS-mediated recovery of elongation from arrest - Homo sapiens [Reaction:R-HSA-113409] Abortive termination of early transcription elongation by DSIF:NELF - Homo sapiens [Reaction:R-HSA-112395] Abortive termination of elongation after arrest - Homo sapiens [Reaction:R-HSA-113429] Elongating transcript encounters a lesion in the template - Homo sapiens [Reaction:R-HSA-75862] Fall Back to Closed Pre-initiation Complex - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2021-12-08
literatureReference	[LiteratureReference:9027356] Structure and function of RNA polymerase II
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	RNA Polymerase II Pre-transcription Events
orthologousEvent	[Pathway:R-PFA-674695] RNA Polymerase II Pre-transcription Events - Plasmodium falciparum [Pathway:R-SCE-674695] RNA Polymerase II Pre-transcription Events - Saccharomyces cerevisiae [Pathway:R-SPO-674695] RNA Polymerase II Pre-transcription Events - Schizosaccharomyces pombe [Pathway:R-DDI-674695] RNA Polymerase II Pre-transcription Events - Dictyostelium discoideum [Pathway:R-CEL-674695] RNA Polymerase II Pre-transcription Events - Caenorhabditis elegans [Pathway:R-DME-674695] RNA Polymerase II Pre-transcription Events - Drosophila melanogaster [Pathway:R-GGA-674695] RNA Polymerase II Pre-transcription Events - Gallus gallus [Pathway:R-XTR-674695] RNA Polymerase II Pre-transcription Events - Xenopus tropicalis [Pathway:R-DRE-674695] RNA Polymerase II Pre-transcription Events - Danio rerio [Pathway:R-SSC-674695] RNA Polymerase II Pre-transcription Events - Sus scrofa [Pathway:R-BTA-674695] RNA Polymerase II Pre-transcription Events - Bos taurus [Pathway:R-CFA-674695] RNA Polymerase II Pre-transcription Events - Canis familiaris [Pathway:R-RNO-674695] RNA Polymerase II Pre-transcription Events - Rattus norvegicus [Pathway:R-MMU-674695] RNA Polymerase II Pre-transcription Events - Mus musculus
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-674695
summation	[Summation:9027345] For initiation, Pol II assembles with the general transcript...
updateTrackers	[UpdateTracker:9784402] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v54:[updateContainedRLE] [UpdateTracker:9781318] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v61:[updateContainedRLE] [UpdateTracker:9782837] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v58:[updateContainedRLE] [UpdateTracker:9787557] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v44:[updateContainedRLE] [UpdateTracker:9783270] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v57:[updateContainedRLE] [UpdateTracker:9783882] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v55:[updateContainedRLE] [UpdateTracker:9780486] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v63:[addLiteratureReference, addSummation] [UpdateTracker:9775301] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v79:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9784402] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v54:[updateContainedRLE] [UpdateTracker:9781318] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v61:[updateContainedRLE] [UpdateTracker:9782837] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v58:[updateContainedRLE] [UpdateTracker:9787557] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v44:[updateContainedRLE] [UpdateTracker:9783270] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v57:[updateContainedRLE] [UpdateTracker:9783882] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v55:[updateContainedRLE] [UpdateTracker:9780486] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v63:[addLiteratureReference, addSummation] [UpdateTracker:9775301] Update Tracker - [Pathway:674695] RNA Polymerase II Pre-transcription Events - v79:[updateContainedRLE]
(replacementInstances)	[Deleted:8985725] Deletion of instance: 112387 [Deleted:2076699] Deletion of instance: 112386
(hasEvent)	[Pathway:R-HSA-73857] RNA Polymerase II Transcription

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