Reactome | RNA Polymerase II Pre-transcription Events

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RNA Polymerase II Pre-transcription Events Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10647684
displayName	RNA Polymerase II Pre-transcription Events
eventOf	[Pathway:R-DRE-73857] RNA Polymerase II Transcription - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-73946] Abortive initiation after formation of the first phosphodiester bond - Danio rerio [Reaction:R-DRE-75891] Abortive Initiation After Second Transition - Danio rerio [Reaction:R-DRE-75856] Abortive Initiation Before Second Transition - Danio rerio [Reaction:R-DRE-112434] Formation of DSIF complex - Danio rerio [Reaction:R-DRE-112429] Formation of FACT complex - Danio rerio [Reaction:R-DRE-112430] Formation of P-TEFb complex - Danio rerio [Reaction:R-DRE-112392] Resumption of elongation after recovery from pausing - Danio rerio [Reaction:R-DRE-113411] 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing - Danio rerio [Reaction:R-DRE-113414] 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest - Danio rerio [Reaction:R-DRE-113413] TFIIS-mediated recovery of elongation from arrest - Danio rerio [Reaction:R-DRE-113409] Abortive termination of early transcription elongation by DSIF:NELF - Danio rerio [Reaction:R-DRE-112395] Abortive termination of elongation after arrest - Danio rerio [Reaction:R-DRE-75862] Fall Back to Closed Pre-initiation Complex - Danio rerio
inferredFrom	[Pathway:R-HSA-674695] RNA Polymerase II Pre-transcription Events - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RNA Polymerase II Pre-transcription Events
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-674695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-73857] RNA Polymerase II Transcription
(inferredTo)	[Pathway:R-HSA-674695] RNA Polymerase II Pre-transcription Events

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