Reactome | USP33 deubiquitinates CCP110,ARRB

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USP33 deubiquitinates CCP110,ARRB Show undefined attributes

authored	[InstanceEdit:5688416] Jupe, Steve, 2015-04-16
catalystActivity	[CatalystActivity:5696988] cysteine-type deubiquitinase activity of USP33:PolyUb-CCP110,PolyUb-ARRB1,PolyUb-ARRB2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5696937] Jupe, Steve, 2015-06-01
dbId	5696945
displayName	USP33 deubiquitinates CCP110,ARRB
edited	[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
eventOf	[Pathway:R-HSA-5689880] Ub-specific processing proteases - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-HSA-6783034] USP33:PolyUb-CCP110,PolyUb-ARRB1,PolyUb-ARRB2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5696941] USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110 [LiteratureReference:5696967] Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
modified	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
name	USP33 deubiquitinates CCP110,ARRB
orthologousEvent	[Reaction:R-DME-5696945] USP33 deubiquitinates CCP110,ARRB - Drosophila melanogaster [Reaction:R-GGA-5696945] USP33 deubiquitinates CCP110,ARRB - Gallus gallus [Reaction:R-XTR-5696945] USP33 deubiquitinates CCP110,ARRB - Xenopus tropicalis [Reaction:R-SSC-5696945] USP33 deubiquitinates CCP110,ARRB - Sus scrofa [Reaction:R-BTA-5696945] USP33 deubiquitinates CCP110,ARRB - Bos taurus [Reaction:R-CFA-5696945] USP33 deubiquitinates CCP110,ARRB - Canis familiaris [Reaction:R-RNO-5696945] USP33 deubiquitinates CCP110,ARRB - Rattus norvegicus [Reaction:R-MMU-5696945] USP33 deubiquitinates CCP110,ARRB - Mus musculus
output	[DefinedSet:R-HSA-5689096] PolyUb [cytosol] [Complex:R-HSA-6783074] USP33:CCP110,ARRB1,ARRB2 [cytosol]
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8871339] Meldal, Birgit, 2016-05-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5696945
summation	[Summation:5696983] USP33 regulates centrosome duplication by mediating deubiqui...

Referrals

(hasEvent)

[Pathway:R-HSA-5689880] Ub-specific processing proteases