Reactome | ESD dimer hydrolyses S-FGSH to GSH

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ESD dimer hydrolyses S-FGSH to GSH Show undefined attributes

authored	[InstanceEdit:5693803] Jassal, Bijay, 2015-05-18
catalystActivity	[CatalystActivity:5693721] S-formylglutathione hydrolase activity of ESD dimer [endoplasmic reticulum lumen]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:5693720] Jassal, Bijay, 2015-05-18
crossReference	[DatabaseIdentifier:12668253] RHEA:14962
dbId	5693724
displayName	ESD dimer hydrolyses S-FGSH to GSH
edited	[InstanceEdit:5693803] Jassal, Bijay, 2015-05-18
eventOf	[Pathway:R-HSA-156590] Glutathione conjugation - Homo sapiens
input	[SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-5693723] S-FGSH [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5693725] Esterase D: a new human polymorphism [LiteratureReference:5693726] Identity of the polymorphisms for esterase D and S-formylglutathione hydrolase in red blood cells
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	ESD dimer hydrolyses S-FGSH to GSH
orthologousEvent	[Reaction:R-SCE-5693724] ESD dimer hydrolyses S-FGSH to GSH - Saccharomyces cerevisiae [Reaction:R-DDI-5693724] ESD dimer hydrolyses S-FGSH to GSH - Dictyostelium discoideum [Reaction:R-CEL-5693724] ESD dimer hydrolyses S-FGSH to GSH - Caenorhabditis elegans [Reaction:R-DME-5693724] ESD dimer hydrolyses S-FGSH to GSH - Drosophila melanogaster [Reaction:R-GGA-5693724] ESD dimer hydrolyses S-FGSH to GSH - Gallus gallus [Reaction:R-XTR-5693724] ESD dimer hydrolyses S-FGSH to GSH - Xenopus tropicalis [Reaction:R-DRE-5693724] ESD dimer hydrolyses S-FGSH to GSH - Danio rerio [Reaction:R-SSC-5693724] ESD dimer hydrolyses S-FGSH to GSH - Sus scrofa [Reaction:R-BTA-5693724] ESD dimer hydrolyses S-FGSH to GSH - Bos taurus [Reaction:R-CFA-5693724] ESD dimer hydrolyses S-FGSH to GSH - Canis familiaris [Reaction:R-RNO-5693724] ESD dimer hydrolyses S-FGSH to GSH - Rattus norvegicus [Reaction:R-MMU-5693724] ESD dimer hydrolyses S-FGSH to GSH - Mus musculus
output	[SimpleEntity:R-ALL-194712] formate [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-158543] GSH [endoplasmic reticulum lumen]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5693724
summation	[Summation:5693722] S-formylglutathione hydrolase (ESD, esterase D) is a homodim...

Referrals

(hasEvent)

[Pathway:R-HSA-156590] Glutathione conjugation