Reactome | TFR2 dimer binds 2xholoTF

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TFR2 dimer binds 2xholoTF Show undefined attributes

authored	[InstanceEdit:5691161] Jassal, Bijay, 2015-05-05
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:5691161] Jassal, Bijay, 2015-05-05
dbId	5691150
displayName	TFR2 dimer binds 2xholoTF
edited	[InstanceEdit:5691161] Jassal, Bijay, 2015-05-05
eventOf	[Pathway:R-HSA-917977] Transferrin endocytosis and recycling - Homo sapiens
input	2 × [Complex:R-HSA-917889] holoTF [extracellular region] [EntityWithAccessionedSequence:R-HSA-5691118] TFR2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5691142] Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family [LiteratureReference:5691139] Transferrin receptor 2: a new molecule in iron metabolism [LiteratureReference:5691086] The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22 [LiteratureReference:5691119] Non-HFE haemochromatosis
maxDepth	1
modified	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
name	TFR2 dimer binds 2xholoTF
orthologousEvent	[Reaction:R-DRE-5691150] TFR2 dimer binds 2xholoTF - Danio rerio [Reaction:R-SSC-5691150] TFR2 dimer binds 2xholoTF - Sus scrofa [Reaction:R-BTA-5691150] TFR2 dimer binds 2xholoTF - Bos taurus [Reaction:R-RNO-5691150] TFR2 dimer binds 2xholoTF - Rattus norvegicus [Reaction:R-MMU-5691150] TFR2 dimer binds 2xholoTF - Mus musculus
output	[Complex:R-HSA-5691094] TFR2 dimer:2xholoTF [plasma membrane]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8955387] D'Eustachio, Peter, 2017-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5691150
summation	[Summation:5691192] Transferrin receptor 2 (TFR2) is highly expressed in liver a...

Referrals

(hasEvent)

[Pathway:R-HSA-917977] Transferrin endocytosis and recycling

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