Reactome | TFR2 dimer binds 2xholoTF

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10521870
displayName	TFR2 dimer binds 2xholoTF
eventOf	[Pathway:R-SSC-917977] Transferrin endocytosis and recycling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5691150] TFR2 dimer binds 2xholoTF - Homo sapiens
input	2 × [Complex:R-SSC-917889] holoTF [extracellular region] [EntityWithAccessionedSequence:R-SSC-5691118] TFR2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TFR2 dimer binds 2xholoTF
output	[Complex:R-SSC-5691094] TFR2 dimer:2xholoTF [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5691150
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-917977] Transferrin endocytosis and recycling
(inferredTo)	[Reaction:R-HSA-5691150] TFR2 dimer binds 2xholoTF

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