Reactome | 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]

Schema > Complex > Entries

3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[BlackBoxEvent:R-HSA-5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 - Homo sapiens
created	[InstanceEdit:5684256] Shamovsky, Veronica, 2015-03-20
dbId	5684242
displayName	3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-451619] 3xUb-p-S927,S932-NFKB1(1-968) [cytosol] [EntityWithAccessionedSequence:R-HSA-5684259] p-S400,T290-MAP3K8 [cytosol] [EntityWithAccessionedSequence:R-HSA-451661] TNIP2 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Mus musculus [Complex:R-RNO-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Rattus norvegicus [Complex:R-BTA-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Bos taurus [Complex:R-SSC-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Sus scrofa [Complex:R-DRE-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Danio rerio [Complex:R-XTR-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Xenopus tropicalis [Complex:R-GGA-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - Gallus gallus
isChimeric	false
maxDepth	2
modified	[InstanceEdit:9645200] Shamovsky, Veronica, 2019-05-06
name	3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2
negativelyRegulates	[NegativeRegulation:R-HSA-5692833] Negative regulation by '3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]'
producedByEvent	[Reaction:R-HSA-5684250] SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5684242
updateTrackers	[UpdateTracker:9900400] Update Tracker - [Complex:5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - v69:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9900400] Update Tracker - [Complex:5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] - v69:[add_removeHasComponent]
(regulator)	[NegativeRegulation:R-HSA-5692833] Negative regulation by '3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]'
(output)	[Reaction:R-HSA-5684250] SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2
(input)	[BlackBoxEvent:R-HSA-5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105

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