Reactome | ABCC2 transports BMG,BDG from cytosol to extracellular region

Schema > Reaction > Entries

ABCC2 transports BMG,BDG from cytosol to extracellular region Show undefined attributes

authored	[InstanceEdit:5679023] Jassal, Bijay, 2015-03-02
catalystActivity	[CatalystActivity:5679028] bilirubin transmembrane transporter activity of ABCC2 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:5679023] Jassal, Bijay, 2015-03-02
dbId	5679041
diseaseReaction	[FailedReaction:R-HSA-5679031] Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region - Homo sapiens
displayName	ABCC2 transports BMG,BDG from cytosol to extracellular region
edited	[InstanceEdit:1454911] Jassal, Bijay, 2011-07-19
eventOf	[Pathway:R-HSA-189483] Heme degradation - Homo sapiens
followingEvent	[Reaction:R-HSA-9661820] Bacterial GUSB hydrolyses BDG to BIL - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-5679042] BMG,BDG [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6810312] Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	ABCC2 transports BMG,BDG from cytosol to extracellular region
orthologousEvent	[Reaction:R-SCE-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Saccharomyces cerevisiae [Reaction:R-SPO-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Schizosaccharomyces pombe [Reaction:R-DDI-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Dictyostelium discoideum [Reaction:R-CEL-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Caenorhabditis elegans [Reaction:R-DME-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Drosophila melanogaster [Reaction:R-GGA-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Gallus gallus [Reaction:R-XTR-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Xenopus tropicalis [Reaction:R-DRE-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Danio rerio [Reaction:R-SSC-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Sus scrofa [Reaction:R-BTA-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Bos taurus [Reaction:R-CFA-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Canis familiaris [Reaction:R-RNO-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Rattus norvegicus [Reaction:R-MMU-5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-5679034] BMG,BDG [extracellular region] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-9661446] BMG, BDG translocates from ER lumen to cytosol - Homo sapiens
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6810308] D'Eustachio, Peter, 2015-11-16
revised	[InstanceEdit:9661807] Jassal, Bijay, 2019-09-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5679041
summation	[Summation:5679035] Canalicular multispecific organic anion transporter 1 (ABCC2...
updateTrackers	[UpdateTracker:9777499] Update Tracker - [Reaction:5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - v71:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9777499] Update Tracker - [Reaction:5679041] ABCC2 transports BMG,BDG from cytosol to extracellular region - v71:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5679031] Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region
(hasEvent)	[Pathway:R-HSA-189483] Heme degradation
(precedingEvent)	[Reaction:R-HSA-9661820] Bacterial GUSB hydrolyses BDG to BIL

Cite Us!