Reactome | Thr-180 of ULK1 is phosphorylated

Schema > BlackBoxEvent > Entries

Thr-180 of ULK1 is phosphorylated Show undefined attributes

authored	[InstanceEdit:5671581] Jupe, Steve, 2015-02-02
catalystActivity	[CatalystActivity:5675849] protein serine/threonine kinase activity of p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5672023] Jupe, Steve, 2015-02-04
dbId	5672008
displayName	Thr-180 of ULK1 is phosphorylated
edited	[InstanceEdit:5692984] Jupe, Steve, 2015-05-13
eventOf	[Pathway:R-HSA-1632852] Macroautophagy - Homo sapiens
followingEvent	[Reaction:R-HSA-8876446] p-ULK1 phosphorylates DENND3 - Homo sapiens [Reaction:R-HSA-5675868] ULK1 phosphorylates ATG13 and RB1CC1 - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-5673748] p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5675851] The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Thr-180 of ULK1 is phosphorylated
orthologousEvent	[BlackBoxEvent:R-SCE-5672008] Thr-180 of ULK1 is phosphorylated - Saccharomyces cerevisiae [BlackBoxEvent:R-SPO-5672008] Thr-180 of ULK1 is phosphorylated - Schizosaccharomyces pombe [BlackBoxEvent:R-DDI-5672008] Thr-180 of ULK1 is phosphorylated - Dictyostelium discoideum [BlackBoxEvent:R-CEL-5672008] Thr-180 of ULK1 is phosphorylated - Caenorhabditis elegans [BlackBoxEvent:R-DME-5672008] Thr-180 of ULK1 is phosphorylated - Drosophila melanogaster [BlackBoxEvent:R-GGA-5672008] Thr-180 of ULK1 is phosphorylated - Gallus gallus [BlackBoxEvent:R-XTR-5672008] Thr-180 of ULK1 is phosphorylated - Xenopus tropicalis [BlackBoxEvent:R-DRE-5672008] Thr-180 of ULK1 is phosphorylated - Danio rerio [BlackBoxEvent:R-SSC-5672008] Thr-180 of ULK1 is phosphorylated - Sus scrofa [BlackBoxEvent:R-BTA-5672008] Thr-180 of ULK1 is phosphorylated - Bos taurus [BlackBoxEvent:R-CFA-5672008] Thr-180 of ULK1 is phosphorylated - Canis familiaris [BlackBoxEvent:R-RNO-5672008] Thr-180 of ULK1 is phosphorylated - Rattus norvegicus [BlackBoxEvent:R-MMU-5672008] Thr-180 of ULK1 is phosphorylated - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-5675826] p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol]
precedingEvent	[Reaction:R-HSA-5665868] AMPK (complex) phosphorylates ULK1 (complex) - Homo sapiens
releaseDate	2015-06-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693008] Tooze, Sharon A, 2015-05-13 [InstanceEdit:6793656] Klionsky, Daniel J, 2015-09-03
revised	[InstanceEdit:9638297] Varusai, Thawfeek, 2019-03-05
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5672008
summation	[Summation:5672018] ULK1 phosphorylation activates its kinase activity and leads...

Referrals

(precedingEvent)	[Reaction:R-HSA-8876446] p-ULK1 phosphorylates DENND3 [Reaction:R-HSA-5675868] ULK1 phosphorylates ATG13 and RB1CC1
(hasEvent)	[Pathway:R-HSA-1632852] Macroautophagy

Cite Us!