Reactome | Dopachrome is transformed to DHICA by DCT

Schema > Reaction > Entries

Dopachrome is transformed to DHICA by DCT Show undefined attributes

authored	[InstanceEdit:5662656] Jupe, Steve, 2015-01-13
catalystActivity	[CatalystActivity:5662688] dopachrome isomerase activity of DCT:2xZn2+ [melanosome membrane]
category	transition
compartment	[Compartment:5668572] melanosome lumen [Compartment:5668575] melanosome membrane
created	[InstanceEdit:5662656] Jupe, Steve, 2015-01-13
crossReference	[DatabaseIdentifier:12668130] RHEA:13042 [DatabaseIdentifier:9942551] RHEA:13042
dbId	5662660
displayName	Dopachrome is transformed to DHICA by DCT
edited	[InstanceEdit:5673776] Jupe, Steve, 2015-02-10
eventOf	[Pathway:R-HSA-5662702] Melanin biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-8878581] TYRP1 oxidises DHICA to IQCA - Homo sapiens [BlackBoxEvent:R-HSA-5663050] DHI and DHICA polymerize forming eumelanin - Homo sapiens
input	[SimpleEntity:R-ALL-5662665] Dopachrome [melanosome lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5662655] Functional analysis of the slaty gene product (TRP2) as dopachrome tautomerase and the effect of a point mutation on its catalytic function
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Dopachrome is transformed to DHICA by DCT L-dopachrome => 5,6-dihydroxyindole-2-carboxylate
orthologousEvent	[Reaction:R-GGA-5662660] Dopachrome is transformed to DHICA by DCT - Gallus gallus [Reaction:R-DDI-5662660] Dopachrome is transformed to DHICA by DCT - Dictyostelium discoideum [Reaction:R-CEL-5662660] Dopachrome is transformed to DHICA by DCT - Caenorhabditis elegans [Reaction:R-XTR-5662660] Dopachrome is transformed to DHICA by DCT - Xenopus tropicalis [Reaction:R-DRE-5662660] Dopachrome is transformed to DHICA by DCT - Danio rerio [Reaction:R-SSC-5662660] Dopachrome is transformed to DHICA by DCT - Sus scrofa [Reaction:R-BTA-5662660] Dopachrome is transformed to DHICA by DCT - Bos taurus [Reaction:R-CFA-5662660] Dopachrome is transformed to DHICA by DCT - Canis familiaris [Reaction:R-RNO-5662660] Dopachrome is transformed to DHICA by DCT - Rattus norvegicus [Reaction:R-MMU-5662660] Dopachrome is transformed to DHICA by DCT - Mus musculus
output	[SimpleEntity:R-ALL-5662670] DHICA [melanosome lumen]
precedingEvent	[Reaction:R-HSA-5672019] Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa - Homo sapiens
releaseDate	2015-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5674576] Ito, Shosuke, 2015-02-13 [InstanceEdit:5674585] d'Ischia, Marco, 2015-02-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5662660
summation	[Summation:5662721] Dopachrome is converted to DHICA by DCT (Dopachrome tautomer...

Referrals

(hasEvent)	[Pathway:R-HSA-5662702] Melanin biosynthesis
(precedingEvent)	[Reaction:R-HSA-8878581] TYRP1 oxidises DHICA to IQCA [BlackBoxEvent:R-HSA-5663050] DHI and DHICA polymerize forming eumelanin