Reactome | MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)

Schema > Reaction > Entries

authored	[InstanceEdit:5660523] May, Bruce, 2014-12-27
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5660497] May, Bruce, 2015-01-04
dbId	5660479
displayName	MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)
edited	[InstanceEdit:5660523] May, Bruce, 2014-12-27
eventOf	[Pathway:R-HSA-5660489] MTF1 activates gene expression - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-5660530] Expression of SNCB - Homo sapiens
input	[Complex:R-HSA-5660456] MTF1 dimer:12Zn2+ [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5660406] SNCB gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5660170] Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)
output	[Complex:R-HSA-5660451] MTF1 dimer:12Zn2+:SNCB gene [nucleoplasm]
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8955431] Brown, David R, 2017-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5660479
summation	[Summation:5676002] The MTF1:zinc complex binds a metal response element in the ...

(hasEvent)	[Pathway:R-HSA-5660489] MTF1 activates gene expression
(precedingEvent)	[BlackBoxEvent:R-HSA-5660530] Expression of SNCB

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