MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)

Stable Identifier
R-HSA-5660479
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein)
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The MTF1:zinc complex binds a metal response element in the promoter of the beta-synuclein (SNCB) gene and activates transcription in response to zinc (McHugh et al. 2011).
Literature References
PubMed ID Title Journal Year
21386983 Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1

McHugh, PC, Wright, JA, Brown, DR

PLoS ONE 2011
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Authored
May, B  (2014-12-28)
Reviewed
Brown, DR  (2017-01-12)
Created
May, B  (2015-01-05)
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