Reactome | Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

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Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654718] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5654202] Rothfels, Karen, 2014-12-03
dbId	5654187
displayName	Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
hasComponent	[Complex:R-HSA-5654191] Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-74787] PIK3CA [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Mus musculus [Complex:R-RNO-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Canis familiaris [Complex:R-BTA-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Bos taurus [Complex:R-SSC-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Sus scrofa [Complex:R-DRE-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Danio rerio [Complex:R-XTR-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Gallus gallus [Complex:R-DME-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	7
memberOf	[DefinedSet:R-HSA-2316432] Activator:PI3K [plasma membrane] - Homo sapiens
name	Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K
producedByEvent	[Reaction:R-HSA-5654662] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5654187
updateTrackers	[UpdateTracker:9893400] Update Tracker - [Complex:5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9898021] Update Tracker - [Complex:5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - v63:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9893400] Update Tracker - [Complex:5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9898021] Update Tracker - [Complex:5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] - v63:[updateContainedComponent]
(normalEntity)	[EntityFunctionalStatus:5655300] gain_of_function of Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
(physicalEntity)	[CatalystActivity:5654718] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]
(output)	[Reaction:R-HSA-5654662] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA
(hasMember)	[DefinedSet:R-HSA-2316432] Activator:PI3K [plasma membrane]

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