Reactome | Damaged dsDNA becomes damaged DNA template

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5652138] Orlic-Milacic, Marija, 2014-11-28
dbId	5652137
displayName	Damaged dsDNA becomes damaged DNA template
edited	[InstanceEdit:5656172] Orlic-Milacic, Marija, 2014-12-11
eventOf	[Pathway:R-HSA-110314] Recognition of DNA damage by PCNA-containing replication complex - Homo sapiens
followingEvent	[Reaction:R-HSA-5655483] USP1 autocleavage - Homo sapiens [Reaction:R-HSA-5651992] PCNA-containing replication complex binds damaged dsDNA - Homo sapiens
input	[DefinedSet:R-HSA-5652135] Damaged dsDNA [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110567] Error-prone DNA polymerases: novel structures and the benefits of infidelity.
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Damaged dsDNA becomes damaged DNA template
output	[DefinedSet:R-HSA-5651987] Damaged DNA Template [nucleoplasm]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5663080] Borowiec, James, 2015-01-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5652137
summation	[Summation:5652136] If a damaged double strand DNA (dsDNA) is not repaired prior...

(hasEvent)	[Pathway:R-HSA-110314] Recognition of DNA damage by PCNA-containing replication complex
(precedingEvent)	[Reaction:R-HSA-5655483] USP1 autocleavage [Reaction:R-HSA-5651992] PCNA-containing replication complex binds damaged dsDNA

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