Reactome | PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G

Schema > Reaction > Entries

authored	[InstanceEdit:5621479] Garapati, P V, 2014-08-29
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5621373] Garapati, P V, 2014-08-29
dbId	5621356
displayName	PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G
edited	[InstanceEdit:5621479] Garapati, P V, 2014-08-29
eventOf	[Pathway:R-HSA-5621480] Dectin-2 family - Homo sapiens
followingEvent	[Reaction:R-HSA-5621363] SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-5621346] Plcg1 binds p-Y348,352,525,526-Syk - Mus musculus
input	[Complex:R-HSA-5621160] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] [EntityWithAccessionedSequence:R-HSA-984806] PLCG2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PLCG1 binds p-6Y-SYK:p-Y65,Y76-FCER1G
output	[Complex:R-HSA-5621157] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane]
precedingEvent	[Reaction:R-HSA-5621370] SYK autophosphorylates - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5621356
summation	[Summation:5621350] Phospholipase C-gamma (PLCG) binds to phosphorylated Tyr-348...

(hasEvent)	[Pathway:R-HSA-5621480] Dectin-2 family
(precedingEvent)	[Reaction:R-HSA-5621363] SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2
(inferredTo)	[Reaction:R-MMU-5621346] Plcg1 binds p-Y348,352,525,526-Syk

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