Reactome | PLCG2 translocates from cytosol to plasma membrane

Schema > Reaction > Entries

PLCG2 translocates from cytosol to plasma membrane Show undefined attributes

authored	[InstanceEdit:5621479] Garapati, P V, 2014-08-29
category	dissociation
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5621373] Garapati, P V, 2014-08-29
dbId	5621347
displayName	PLCG2 translocates from cytosol to plasma membrane
edited	[InstanceEdit:5621479] Garapati, P V, 2014-08-29
eventOf	[Pathway:R-HSA-5621480] Dectin-2 family - Homo sapiens
input	[Complex:R-HSA-5621158] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5607205] Tyrosine phosphorylation and translocation of phospholipase C-gamma 2 in polymorphonuclear leukocytes treated with pervanadate [LiteratureReference:1169037] Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling
maxDepth	1
modified	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
name	PLCG2 translocates from cytosol to plasma membrane
orthologousEvent	[Reaction:R-RNO-5621347] PLCG2 translocates from cytosol to plasma membrane - Rattus norvegicus [Reaction:R-BTA-5621347] PLCG2 translocates from cytosol to plasma membrane - Bos taurus [Reaction:R-CFA-5621347] PLCG2 translocates from cytosol to plasma membrane - Canis familiaris [Reaction:R-MMU-5621347] PLCG2 translocates from cytosol to plasma membrane - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-5607640] p-Y753,Y759-PLCG2 [plasma membrane] [Complex:R-HSA-5621160] pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane]
precedingEvent	[Reaction:R-HSA-5621363] SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5621347
summation	[Summation:5621372] Tyrosine-phosphorylated Phospholipase C-gamma 2 (PLCG2) tran...

Referrals

(hasEvent)

[Pathway:R-HSA-5621480] Dectin-2 family

Cite Us!