Reactome | FKBP5 [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9909487] FKBP5:CHUK [cytosol] - Homo sapiens [Complex:R-HSA-9909488] IFI44L, IFI44:FKBP5 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9909510] FKBP5 binds CHUK:IKBKB:IKBKG - Homo sapiens [Reaction:R-HSA-5618105] FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein - Homo sapiens [Reaction:R-HSA-9909519] IFI44, IFI44L binds FKBP5 - Homo sapiens
created	[InstanceEdit:5618086] Shamovsky, Veronica, 2014-08-18
dbId	5618096
displayName	FKBP5 [cytosol]
endCoordinate	457
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5618096] Fkbp5 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-5618096] FKBP5 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-5618096] FKBP5 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-5618096] FKBP5 [cytosol] - Sus scrofa [GenomeEncodedEntity:R-DRE-5618096] Ghost homologue of FKBP5 [cytosol] - Danio rerio [GenomeEncodedEntity:R-XTR-5618096] Ghost homologue of FKBP5 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-5618096] FKBP5 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-5618096] Fkbp59 [cytosol] - Drosophila melanogaster [GenomeEncodedEntity:R-DDI-5618096] Ghost homologue of FKBP5 [cytosol] - Dictyostelium discoideum [GenomeEncodedEntity:R-SPO-5618096] Ghost homologue of FKBP5 [cytosol] - Schizosaccharomyces pombe [GenomeEncodedEntity:R-SCE-5618096] Ghost homologue of FKBP5 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-5618096] FKBP35 [cytosol] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	FKBP5 FKBP51 51 kDa FK506-binding protein AIG6 54 kDa progesterone receptor-associated immunophilin
producedByEvent	[Reaction:R-HSA-5618073] FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein - Homo sapiens [BlackBoxEvent:R-HSA-9022728] FKBP5 gene expression is inhibited by MECP2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q13451] UniProt:Q13451 FKBP5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5618096
startCoordinate	1

(input)	[Reaction:R-HSA-9909519] IFI44, IFI44L binds FKBP5 [Reaction:R-HSA-9909510] FKBP5 binds CHUK:IKBKB:IKBKG [Reaction:R-HSA-5618105] FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein
(hasComponent)	[Complex:R-HSA-9909488] IFI44L, IFI44:FKBP5 [cytosol] [Complex:R-HSA-9909487] FKBP5:CHUK [cytosol] [Complex:R-HSA-5618095] HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] [Complex:R-HSA-5618074] HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol]
(output)	[Reaction:R-HSA-5618073] FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein [BlackBoxEvent:R-HSA-9022728] FKBP5 gene expression is inhibited by MECP2

FKBP5 [cytosol] Show undefined attributes

Referrals