Reactome | TICAM1 S186L [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5607968] Shamovsky, Veronica, 2014-07-14
crossReference	[DatabaseIdentifier:12021025] Mondo:0003778
dbId	5607964
disease	[Disease:5228860] primary immunodeficiency disease
displayName	TICAM1 S186L [cytosol]
endCoordinate	712
hasModifiedResidue	[ReplacedResidue:5607967] L-serine 186 replaced with L-leucine
inDisease	true
literatureReference	[LiteratureReference:5602458] Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
maxDepth	1
memberOf	[DefinedSet:R-HSA-5607960] TICAM1 variants [cytosol] - Homo sapiens
modified	[InstanceEdit:9967564] D'Eustachio, Peter, 2025-10-02
name	TICAM1 S186L
referenceEntity	[ReferenceGeneProduct:uniprot:Q8IUC6] UniProt:Q8IUC6 TICAM1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5607964
startCoordinate	1
updateTrackers	[UpdateTracker:9972245] Update Tracker - [EntityWithAccessionedSequence:5607964] TICAM1 S186L [cytosol] - v95:[modifyEndCoordinate]

(updatedInstance)	[UpdateTracker:9972245] Update Tracker - [EntityWithAccessionedSequence:5607964] TICAM1 S186L [cytosol] - v95:[modifyEndCoordinate]
(hasMember)	[DefinedSet:R-HSA-5607960] TICAM1 variants [cytosol]

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