Reactome | PROCR binds Protein C

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PROCR binds Protein C Show undefined attributes

authored	[InstanceEdit:5607780] Jupe, Steve, 2014-07-14
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:5591039] Jupe, Steve, 2014-06-11
dbId	5591052
displayName	PROCR binds Protein C
edited	[InstanceEdit:5627264] Jupe, Steve, 2014-07-28
eventOf	[Pathway:R-HSA-140875] Common Pathway of Fibrin Clot Formation - Homo sapiens
followingEvent	[Reaction:R-HSA-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5591027] PROCR [plasma membrane] [Complex:R-HSA-141043] Protein C [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5591083] Endothelial cell protein C receptor plays an important role in protein C activation in vivo
modified	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name	PROCR binds Protein C EPCR binds Protein C
orthologousEvent	[Reaction:R-CFA-5591052] PROCR binds Protein C - Canis familiaris [Reaction:R-GGA-5591052] PROCR binds Protein C - Gallus gallus [Reaction:R-SSC-5591052] PROCR binds Protein C - Sus scrofa [Reaction:R-BTA-5591052] PROCR binds Protein C - Bos taurus [Reaction:R-RNO-5591052] PROCR binds Protein C - Rattus norvegicus [Reaction:R-MMU-5591052] PROCR binds Protein C - Mus musculus
output	[Complex:R-HSA-5603321] PROCR:Protein C [plasma membrane]
regulatedBy	[NegativeRegulation:R-HSA-5610119] Negative regulation by 'PROCR(18-?):Activated protein C [extracellular region]'
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5627265] Mumford, Andrew, 2014-09-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5591052
summation	[Summation:5591094] Physiological activation of protein C on the endothelial cel...
systematicName	PROCR binds Protein C

Referrals

(hasEvent)	[Pathway:R-HSA-140875] Common Pathway of Fibrin Clot Formation
(precedingEvent)	[Reaction:R-HSA-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C