Reactome | TECR,TECRL dehydrogenate TOD-CoA to ST-CoA

Schema > Reaction > Entries

TECR,TECRL dehydrogenate TOD-CoA to ST-CoA Show undefined attributes

authored	[InstanceEdit:548846] D'Eustachio, P, 2010-03-14
catalystActivity	[CatalystActivity:548793] very-long-chain fatty acyl-CoA dehydrogenase activity of TECR,TECRL [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:548837] D'Eustachio, P, 2010-03-14
crossReference	[DatabaseIdentifier:12668388] RHEA:35353
dbId	548831
displayName	TECR,TECRL dehydrogenate TOD-CoA to ST-CoA
edited	[InstanceEdit:5678222] D'Eustachio, Peter, 2015-02-21
eventOf	[Pathway:R-HSA-75876] Synthesis of very long-chain fatty acyl-CoAs - Homo sapiens
followingEvent	[Reaction:R-HSA-8847579] SCD5 desaturates ST-CoA to OLE-CoA - Homo sapiens [Reaction:R-HSA-5690565] SCD desaturates ST-CoA to OLE-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol] [SimpleEntity:R-ALL-548809] TOD-CoA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:548718] Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (2E)-octadecenoyl-CoA + H(+) + NADPH => NADP(+) + octadecanoyl-CoA trans-octadec-2-enoyl-CoA + NADPH + H+ => stearoyl-CoA + NADP+
orthologousEvent	[Reaction:R-PFA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Plasmodium falciparum [Reaction:R-SCE-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Saccharomyces cerevisiae [Reaction:R-SPO-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Schizosaccharomyces pombe [Reaction:R-DDI-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Dictyostelium discoideum [Reaction:R-CEL-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Caenorhabditis elegans [Reaction:R-DME-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Drosophila melanogaster [Reaction:R-GGA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Gallus gallus [Reaction:R-XTR-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Xenopus tropicalis [Reaction:R-DRE-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Danio rerio [Reaction:R-SSC-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Sus scrofa [Reaction:R-BTA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Bos taurus [Reaction:R-CFA-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Canis familiaris [Reaction:R-RNO-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Rattus norvegicus [Reaction:R-MMU-548831] TECR,TECRL dehydrogenate TOD-CoA to ST-CoA - Mus musculus
output	[SimpleEntity:R-ALL-29366] NADP+ [cytosol] [SimpleEntity:R-ALL-428139] ST-CoA [cytosol]
precedingEvent	[Reaction:R-HSA-5676637] PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5678222] D'Eustachio, Peter, 2015-02-21
revised	[InstanceEdit:5676160] Jassal, Bijay, 2015-02-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-548831
summation	[Summation:548804] Trans-2,3-enoyl-CoA reductase (TECR) catalyzes the reaction ...

Referrals

(precedingEvent)	[Reaction:R-HSA-8847579] SCD5 desaturates ST-CoA to OLE-CoA [Reaction:R-HSA-5690565] SCD desaturates ST-CoA to OLE-CoA
(hasEvent)	[Pathway:R-HSA-75876] Synthesis of very long-chain fatty acyl-CoAs