TECR,TECRL dehydrogenate TOD-CoA to ST-CoA

Stable Identifier
R-HSA-548831
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
trans-octadec-2-enoyl-CoA + NADPH + H+ => stearoyl-CoA + NADP+
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Trans-2,3-enoyl-CoA reductase (TECR) catalyzes the reaction of trans-octadec-2-enoyl-CoA and NADPH + H+ to form stearoyl-CoA and NADP+. This activity of TECR protein and its localization to the endoplasmic reticulum membrane was established in studies of transfected cells expressing the protein (Moon and Horton 2003).

Literature References
PubMed ID Title Journal Year
12482854 Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade

Moon, YA, Horton, JD

J Biol Chem 2003
Participants
Participates
Catalyst Activity

very-long-chain-acyl-CoA dehydrogenase activity of TECR,TECRL [endoplasmic reticulum membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!