Reactome | STX1(?-288) [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5250512] D'Eustachio, Peter, 2014-01-25
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	5250513
deleted	[Deleted:5250994] Deletion of instance: 181508
disease	[Disease:3632909] botulism
displayName	STX1(?-288) [plasma membrane]
hasMember	[EntityWithAccessionedSequence:R-HSA-5246518] STX1A(?-288) [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5246519] STX1B(?-288) [plasma membrane] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:5246522] Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin [LiteratureReference:181711] Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release
maxDepth	2
modified	[InstanceEdit:5250516] D'Eustachio, Peter, 2014-01-25
name	STX1(?-288) Syntaxin 1 carboxyterminal fragment
producedByEvent	[Reaction:R-HSA-181567] botC LC cleaves target cell STX1 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-5250513

(replacementInstances)	[Deleted:5250994] Deletion of instance: 181508
(output)	[Reaction:R-HSA-181567] botC LC cleaves target cell STX1

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