Reactome | p-S166-RIPK1:p-S199,227-RIPK3 [cytosol]

Schema > Complex > Entries

p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Polymerisation:R-HSA-5218905] RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils - Homo sapiens [Reaction:R-HSA-9686922] PELI1 binds activated RIPK1:RIPK3 - Homo sapiens
created	[InstanceEdit:5218874] Shamovsky, V, 2013-12-20
dbId	5218870
displayName	p-S166-RIPK1:p-S199,227-RIPK3 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-5218872] p-S166-RIPK1 [cytosol] [EntityWithAccessionedSequence:R-HSA-5218873] p-S199,227-RIPK3 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Mus musculus [Complex:R-RNO-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Rattus norvegicus [Complex:R-CFA-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Canis familiaris [Complex:R-BTA-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Bos taurus [Complex:R-SSC-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Sus scrofa [Complex:R-GGA-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Gallus gallus [Complex:R-DDI-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Dictyostelium discoideum [Complex:R-PFA-5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - Plasmodium falciparum
isChimeric	false
literatureReference	[LiteratureReference:5218869] The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
maxDepth	2
modified	[InstanceEdit:9698669] Shamovsky, Veronica, 2020-08-28
name	p-S166-RIPK1:p-S199,227-RIPK3
producedByEvent	[Reaction:R-HSA-5213466] RIPK3 is phosphorylated - Homo sapiens
repeatedUnitOf	[Polymer:R-HSA-5218908] p-S-RIPK1:p-S199,227-RIPK3 oligomer [cytosol] - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5218870
updateTrackers	[UpdateTracker:9901541] Update Tracker - [Complex:5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - v74:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9901541] Update Tracker - [Complex:5218870] p-S166-RIPK1:p-S199,227-RIPK3 [cytosol] - v74:[modifyName]
(input)	[Reaction:R-HSA-9686922] PELI1 binds activated RIPK1:RIPK3 [Polymerisation:R-HSA-5218905] RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils
(output)	[Reaction:R-HSA-5213466] RIPK3 is phosphorylated
(repeatedUnit)	[Polymer:R-HSA-5218908] p-S-RIPK1:p-S199,227-RIPK3 oligomer [cytosol]

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