Reactome | HSP90AA1 binds p-6Y-VEGFR2

Schema > Reaction > Entries

HSP90AA1 binds p-6Y-VEGFR2 Show undefined attributes

authored	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5218634] Garapati, P V, 2013-12-19
dbId	5218643
displayName	HSP90AA1 binds p-6Y-VEGFR2
edited	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
eventOf	[Pathway:R-HSA-4420097] VEGFA-VEGFR2 Pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-3928647] RHOA:GTP:Mg2+ binds ROCK1,ROCK2 - Homo sapiens [Reaction:R-HSA-5218826] Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-192864] HSP90AA1 [cytosol] [Complex:R-HSA-5218636] VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5218558] Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	HSP90AA1 binds p-6Y-VEGFR2
orthologousEvent	[Reaction:R-GGA-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Gallus gallus [Reaction:R-XTR-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Xenopus tropicalis [Reaction:R-SSC-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Sus scrofa [Reaction:R-BTA-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Bos taurus [Reaction:R-CFA-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Canis familiaris [Reaction:R-RNO-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Rattus norvegicus [Reaction:R-MMU-5218643] HSP90AA1 binds p-6Y-VEGFR2 - Mus musculus
output	[Complex:R-HSA-5218637] VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-5218640] SRC-1 phosphorylates p-Y397-PTK2 - Homo sapiens
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5432673] Welsh, Michael, Berger, Philipp, Ballmer-Hofer, Kurt, 2014-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5218643
summation	[Summation:5218413] Heat-shock protein of 90 kDa (HSP90) a molecular chaperone, ...

Referrals

(hasEvent)	[Pathway:R-HSA-4420097] VEGFA-VEGFR2 Pathway
(precedingEvent)	[Reaction:R-HSA-3928647] RHOA:GTP:Mg2+ binds ROCK1,ROCK2 [Reaction:R-HSA-5218826] Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732