HSP90AA1 binds p-6Y-VEGFR2

Stable Identifier
R-HSA-5218643
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Heat-shock protein of 90 kDa (HSP90) a molecular chaperone, associates with VEGFR2 in response to VEGF. The last 130 amino acids of VEGFR2 C-terminal portion are involved in the association of VEGFR2 with HSP90. HSP90 associated with VEGFR2 is involved in regulating the activity of a Rho-associated protein kinase (ROCK) that is required to phosphorylate FAK on residue S732 (Le Bouef et al. 2004, 2006).
Literature References
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!