Reactome | Positive regulation by 'VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]'

Schema > PositiveRegulation > Entries

created	[InstanceEdit:5218634] Garapati, P V, 2013-12-19
dbId	5218633
displayName	Positive regulation by 'VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]'
modified	[InstanceEdit:9733355] Wu, Guanming, 2021-06-04
regulatedEntity	[Reaction:R-HSA-3928647] RHOA:GTP:Mg2+ binds ROCK1,ROCK2 - Homo sapiens
regulator	[Complex:R-HSA-5218637] VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]
schemaClass	PositiveRegulation
stId	R-HSA-5218633

(regulation)	[RegulationReference:9641764] Positive regulation by 'VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2:SRC-1:HSP90AA1 [plasma membrane]' Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor
(regulatedBy)	[Reaction:R-HSA-3928647] RHOA:GTP:Mg2+ binds ROCK1,ROCK2

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