Reactome | MAP2K1(2-8) [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:5211335] D'Eustachio, Peter, 2013-12-09
crossReference	[DatabaseIdentifier:12020807] Mondo:0005119
dbId	5211342
disease	[Disease:5205706] anthrax disease
displayName	MAP2K1(2-8) [cytosol]
endCoordinate	8
inDisease	true
literatureReference	[LiteratureReference:5211331] Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor [LiteratureReference:5211349] Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
maxDepth	1
modified	[InstanceEdit:5211358] D'Eustachio, Peter, 2013-12-09
name	MAP2K1(2-8) MAP2K1 small LF fragment
producedByEvent	[Reaction:R-HSA-5211340] Anthrax lef cleaves target cell MAP2K1 (MEK1) - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q02750] UniProt:Q02750 MAP2K1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-5211342
startCoordinate	2

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