Reactome | HuR:mRNA complexes [nucleoplasm]

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HuR:mRNA complexes [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-450537] HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-450387] HuR binds the CRM1 nuclear export machinery - Homo sapiens
created	[InstanceEdit:517669] May, B, 2010-02-19
dbId	517615
displayName	HuR:mRNA complexes [nucleoplasm]
hasMember	[Complex:R-HSA-450395] HuR with Unknown Phosphorylation: mRNA Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-517672] HuR with phosphoserine221 and phosphoserine158:mRNA Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-517751] HuR with phosphoserine221 and phosphoserine318:mRNA Complex [nucleoplasm] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-517615] HuR:mRNA complexes [nucleoplasm] - Mus musculus [DefinedSet:R-RNO-517615] HuR:mRNA complexes [nucleoplasm] - Rattus norvegicus [DefinedSet:R-CFA-517615] HuR:mRNA complexes [nucleoplasm] - Canis familiaris [DefinedSet:R-BTA-517615] HuR:mRNA complexes [nucleoplasm] - Bos taurus [DefinedSet:R-SSC-517615] HuR:mRNA complexes [nucleoplasm] - Sus scrofa [DefinedSet:R-DRE-517615] HuR:mRNA complexes [nucleoplasm] - Danio rerio [DefinedSet:R-GGA-517615] HuR:mRNA complexes [nucleoplasm] - Gallus gallus [DefinedSet:R-DME-517615] HuR:mRNA complexes [nucleoplasm] - Drosophila melanogaster
literatureReference	[LiteratureReference:450374] Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2 [LiteratureReference:517773] Tandem phosphorylation of serine 221 and 318 by PKC{delta} coordinates mRNA binding and nucleo-cytoplasmic shuttling of HuR [LiteratureReference:450594] Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
maxDepth	3
modified	[InstanceEdit:5262812] May, B, 2014-02-07
name	HuR:mRNA complexes
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-517615
updateTrackers	[UpdateTracker:9871305] Update Tracker - [DefinedSet:517615] HuR:mRNA complexes [nucleoplasm] - v39:[modifyName] [UpdateTracker:9889039] Update Tracker - [DefinedSet:517615] HuR:mRNA complexes [nucleoplasm] - v48:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9871305] Update Tracker - [DefinedSet:517615] HuR:mRNA complexes [nucleoplasm] - v39:[modifyName] [UpdateTracker:9889039] Update Tracker - [DefinedSet:517615] HuR:mRNA complexes [nucleoplasm] - v48:[modifyName]
(hasComponent)	[Complex:R-HSA-450537] HuR:APRIL:pp32:SET(SETalpha):Nup214(SETbeta):CRM1 [nucleoplasm]
(input)	[Reaction:R-HSA-450387] HuR binds the CRM1 nuclear export machinery

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