Reactome | N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine

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N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine Show undefined attributes

authored	[InstanceEdit:517534] Jupe, S, 2010-02-19
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:517534] Jupe, S, 2010-02-19
dbId	517536
displayName	N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine
edited	[InstanceEdit:532507] Jupe, S, 2010-03-01
eventOf	[Pathway:R-HSA-373076] Class A/1 (Rhodopsin-like receptors) - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-517529] GPR18 [plasma membrane] [SimpleEntity:R-ALL-517533] NAGLY [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:517531] Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine
orthologousEvent	[Reaction:R-CEL-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Caenorhabditis elegans [Reaction:R-GGA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Gallus gallus [Reaction:R-XTR-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Xenopus tropicalis [Reaction:R-SSC-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Sus scrofa [Reaction:R-BTA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Bos taurus [Reaction:R-CFA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Canis familiaris [Reaction:R-RNO-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Rattus norvegicus [Reaction:R-MMU-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Mus musculus
output	[Complex:R-HSA-517528] GPR18:NAGLY [plasma membrane]
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:450112] D'Eustachio, P, 2009-12-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-517536
summation	[Summation:517535] GPR18 (GPRW) is a receptor for the biologically active anand...

Referrals

(hasEvent)	[Pathway:R-HSA-373076] Class A/1 (Rhodopsin-like receptors)
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi

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