Reactome | N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine

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N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10940927
displayName	N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine
eventOf	[Pathway:R-CEL-373076] Class A/1 (Rhodopsin-like receptors) - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-517529] gnrr-4 [plasma membrane] [SimpleEntity:R-ALL-517533] NAGLY [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine
output	[Complex:R-CEL-517528] GPR18:NAGLY [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-517536
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-373076] Class A/1 (Rhodopsin-like receptors)
(precedingEvent)	[Reaction:R-CEL-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
(inferredTo)	[Reaction:R-HSA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine

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