Reactome | HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm]

Schema > Complex > Entries

HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5082369] Acetylated HSF1 dissociates from DNA - Homo sapiens [Reaction:R-HSA-3371518] SIRT1 binds to HSF1 - Homo sapiens
created	[InstanceEdit:5082375] Shamovsky, V, 2013-11-05
dbId	5082373
displayName	HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm]
hasComponent	[Complex:R-HSA-5097240] Ac-K80-HSF1 trimer [nucleoplasm] [DefinedSet:R-HSA-4793834] HSF1 target gene [nucleoplasm] [Complex:R-HSA-5082372] HSP70:DNAJB1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Mus musculus [Complex:R-RNO-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Canis familiaris [Complex:R-BTA-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Bos taurus [Complex:R-SSC-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Sus scrofa [Complex:R-DRE-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Danio rerio [Complex:R-GGA-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Gallus gallus [Complex:R-DME-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - Saccharomyces cerevisiae
isChimeric	false
literatureReference	[LiteratureReference:5082376] Molecular chaperones as HSF1-specific transcriptional repressors
maxDepth	4
modified	[InstanceEdit:5097239] Shamovsky, V, 2013-11-11
name	HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene
producedByEvent	[Reaction:R-HSA-3371554] HSF1 acetylation at Lys80 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5082373
updateTrackers	[UpdateTracker:9892698] Update Tracker - [Complex:5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - v54:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9892698] Update Tracker - [Complex:5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] - v54:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm]
(input)	[Reaction:R-HSA-3371518] SIRT1 binds to HSF1 [Reaction:R-HSA-5082369] Acetylated HSF1 dissociates from DNA
(output)	[Reaction:R-HSA-3371554] HSF1 acetylation at Lys80

© 2026 Reactome

Cite Us!