Reactome | SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm]

Schema > Complex > Entries

SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:5083139] NAD-dependent protein lysine deacetylase activity of SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-3371467] SIRT1 deacetylates HSF1 - Homo sapiens
created	[InstanceEdit:5082392] Shamovsky, V, 2013-11-05
dbId	5082382
displayName	SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm]
hasComponent	[Complex:R-HSA-5082373] HSP70:DNAJB1:Ac-K80-HSF1 trimer:target gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-427531] SIRT1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Mus musculus [Complex:R-RNO-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Canis familiaris [Complex:R-BTA-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Bos taurus [Complex:R-SSC-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Sus scrofa [Complex:R-DRE-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Danio rerio [Complex:R-GGA-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Gallus gallus [Complex:R-DME-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - Saccharomyces cerevisiae
isChimeric	false
maxDepth	5
name	SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene
producedByEvent	[Reaction:R-HSA-3371518] SIRT1 binds to HSF1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5082382
updateTrackers	[UpdateTracker:9892621] Update Tracker - [Complex:5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - v54:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9892621] Update Tracker - [Complex:5082382] SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] - v54:[updateContainedComponent]
(input)	[Reaction:R-HSA-3371467] SIRT1 deacetylates HSF1
(physicalEntity)	[CatalystActivity:5083139] NAD-dependent protein lysine deacetylase activity of SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm]
(output)	[Reaction:R-HSA-3371518] SIRT1 binds to HSF1

© 2026 Reactome

Cite Us!