Reactome | Expression of SALL4

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Expression of SALL4 Show undefined attributes

authored	[InstanceEdit:1013049] May, B, 2010-11-12
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:480249] May, B, 2010-01-27
dbId	480520
displayName	Expression of SALL4
edited	[InstanceEdit:1013049] May, B, 2010-11-12
eventOf	[Pathway:R-HSA-452723] Transcriptional regulation of pluripotent stem cells - Homo sapiens
followingEvent	[Reaction:R-HSA-2972968] SALL4 binds the SALL4 promoter - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2888956] SALL4 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:452744] Characterization and gene expression profiling of five new human embryonic stem cell lines derived in Taiwan [LiteratureReference:480315] Markers that define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos [LiteratureReference:480687] Isolation and characterization of stem cells from the human parathyroid gland [LiteratureReference:994184] A novel SALL4/OCT4 transcriptional feedback network for pluripotency of embryonic stem cells [LiteratureReference:480893] Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4 [LiteratureReference:5244458] Differential roles of Sall4 isoforms in embryonic stem cell pluripotency
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of SALL4
output	[EntityWithAccessionedSequence:R-HSA-452644] SALL4 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2972968] SALL4 binds the SALL4 promoter - Homo sapiens [Reaction:R-HSA-2895778] POU5F1 (OCT4), STAT3 bind the SALL4 promoter - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:R-HSA-5159192] Negative gene expression regulation by 'SALL4:SALL4 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5638451] Positive gene expression regulation by 'POU5F1:STAT3:SALL4 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641208] Positive gene expression regulation by 'POU5F1:STAT3:SALL4 gene [nucleoplasm]' Characterization and gene expression profiling of five new human embryonic stem cell lines derived in Taiwan
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5246708] Wang, Jianlong, 2014-01-22
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-480520
summation	[Summation:480312] The SALL4 gene is transcribed to yield mRNA and the mRNA is ...
updateTrackers	[UpdateTracker:9778279] Update Tracker - [BlackBoxEvent:480520] Expression of SALL4 - v68:[removeCatalystActivity] [UpdateTracker:9785850] Update Tracker - [BlackBoxEvent:480520] Expression of SALL4 - v51:[addCatalystActivity, addRegulator, add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9778279] Update Tracker - [BlackBoxEvent:480520] Expression of SALL4 - v68:[removeCatalystActivity] [UpdateTracker:9785850] Update Tracker - [BlackBoxEvent:480520] Expression of SALL4 - v51:[addCatalystActivity, addRegulator, add_removeInput]
(hasEvent)	[Pathway:R-HSA-452723] Transcriptional regulation of pluripotent stem cells
(precedingEvent)	[Reaction:R-HSA-2972968] SALL4 binds the SALL4 promoter

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