Reactome | HSF1 trimer [nucleoplasm]

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HSF1 trimer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5333048] HSF1:RPA [nucleoplasm] - Homo sapiens [Complex:R-HSA-5082413] HSBP1:HSF1 trimer [nucleoplasm] - Homo sapiens [Complex:R-HSA-5324619] HSF1 trimer:HSP90:FKBP4:PTGES3 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5082387] Phosphorylation of HSF1 at Ser230 induces transactivation - Homo sapiens [Reaction:R-HSA-5082405] Phosphorylation of HSF1 at Ser326 induces transactivation - Homo sapiens [Reaction:R-HSA-5324617] HSP90:FKBP4:PTGES3 binds HSF1 trimer - Homo sapiens [Reaction:R-HSA-5333051] RPA1 binds HSF1 - Homo sapiens [Reaction:R-HSA-4793819] HSF1 trimer binds HSE on the target gene - Homo sapiens [Reaction:R-HSA-3371582] HSBP1 binds HSF1 trimer - Homo sapiens
created	[InstanceEdit:4793801] Shamovsky, V, 2013-10-28
dbId	4793790
displayName	HSF1 trimer [nucleoplasm]
hasComponent	3 × [EntityWithAccessionedSequence:R-HSA-3371416] hC36,103-HSF1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-4793790] HSF1 trimer [nucleoplasm] - Mus musculus [Complex:R-RNO-4793790] HSF1 trimer [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-4793790] HSF1 trimer [nucleoplasm] - Canis familiaris [Complex:R-BTA-4793790] HSF1 trimer [nucleoplasm] - Bos taurus [Complex:R-SSC-4793790] HSF1 trimer [nucleoplasm] - Sus scrofa [Complex:R-DRE-4793790] HSF1 trimer [nucleoplasm] - Danio rerio [Complex:R-GGA-4793790] HSF1 trimer [nucleoplasm] - Gallus gallus [Complex:R-DME-4793790] HSF1 trimer [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-4793790] HSF1 trimer [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-4793790] HSF1 trimer [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-4793790] HSF1 trimer [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-4793790] HSF1 trimer [nucleoplasm] - Saccharomyces cerevisiae
isChimeric	false
literatureReference	[LiteratureReference:4793831] Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription
maxDepth	2
name	HSF1 trimer
producedByEvent	[Reaction:R-HSA-5082391] Trimerization of HSF1 in the nucleus - Homo sapiens [BlackBoxEvent:R-HSA-3371527] HSF1 trimer translocates to the nucleus - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-4793790

Referrals

(hasComponent)	[Complex:R-HSA-5333048] HSF1:RPA [nucleoplasm] [Complex:R-HSA-5082413] HSBP1:HSF1 trimer [nucleoplasm] [Complex:R-HSA-5324619] HSF1 trimer:HSP90:FKBP4:PTGES3 [nucleoplasm] [Complex:R-HSA-4793813] HSF1 trimer:target gene [nucleoplasm]
(input)	[Reaction:R-HSA-5333051] RPA1 binds HSF1 [Reaction:R-HSA-5082387] Phosphorylation of HSF1 at Ser230 induces transactivation [Reaction:R-HSA-4793819] HSF1 trimer binds HSE on the target gene [Reaction:R-HSA-5082405] Phosphorylation of HSF1 at Ser326 induces transactivation [Reaction:R-HSA-3371582] HSBP1 binds HSF1 trimer [Reaction:R-HSA-5324617] HSP90:FKBP4:PTGES3 binds HSF1 trimer
(output)	[Reaction:R-HSA-5082391] Trimerization of HSF1 in the nucleus [BlackBoxEvent:R-HSA-3371527] HSF1 trimer translocates to the nucleus

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