Reactome | APC truncation mutants [cytosol]

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APC truncation mutants [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding - Homo sapiens
created	[InstanceEdit:4791257] Rothfels, K, 2013-10-28
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	4791256
disease	[Disease:1500689] cancer
displayName	APC truncation mutants [cytosol]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-4791251] APC G1309Dfs4 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5251499] APC R1450 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666925] APC C1410* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666993] APC E1151* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666934] APC E1209* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666944] APC E1284* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666981] APC E1286* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666992] APC E1295* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666975] APC E1306* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666987] APC E1309* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666953] APC E1317* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666994] APC E1322* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666995] APC E1345* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666990] APC E1353* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666945] APC E1374* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666978] APC E1379* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666961] APC E1397* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666951] APC E1408* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666960] APC E1451* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666952] APC E1464* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666929] APC E1536* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666963] APC E1544* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666938] APC E1573* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666958] APC E1577* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666947] APC E941* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666979] APC E984* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666930] APC G1288* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666931] APC G1312* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666940] APC G1357* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666971] APC G1412* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666956] APC K1308* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666926] APC K1310* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666950] APC K1363* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666984] APC K993* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666941] APC L1488* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666948] APC L1564* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666959] APC Q1127* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666949] APC Q1294* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666972] APC Q1303* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666998] APC Q1328* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666989] APC Q1367* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666982] APC Q1378* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666962] APC Q1406* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666955] APC Q1429* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666935] APC Q1469* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666946] APC Q767* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666965] APC Q886* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666996] APC R1114* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666932] APC R1386* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666924] APC R213* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666977] APC R232* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666988] APC R283* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666986] APC R302* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666991] APC R332* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666936] APC R405* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666927] APC R499* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666983] APC R554* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666928] APC R564* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666939] APC R805* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666985] APC R876* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666937] APC S1281* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666997] APC S1282* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666970] APC S1315* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666933] APC S1327* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666957] APC S1344* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666943] APC S1346* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666976] APC S1356* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666966] APC S1392* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666942] APC S1400* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666967] APC S1539* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666969] APC S895* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666973] APC S943* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666954] APC W1049* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666964] APC Y1376* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9666980] APC Y935* [cytosol] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-5246654] APC Q1338* [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5246651] APC I1417 fs*2 [cytosol] - Homo sapiens
inDisease	true
maxDepth	2
modified	[InstanceEdit:9667073] Rothfels, Karen, 2019-11-07
name	APC truncation mutants
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-4791256
updateTrackers	[UpdateTracker:9900979] Update Tracker - [CandidateSet:4791256] APC truncation mutants [cytosol] - v71:[addHasCandidate]

Referrals

(input)	[FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding
(diseaseEntity)	[EntityFunctionalStatus:4791276] loss_of_function of APC truncation mutants [cytosol]
(updatedInstance)	[UpdateTracker:9900979] Update Tracker - [CandidateSet:4791256] APC truncation mutants [cytosol] - v71:[addHasCandidate]

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