Reactome | APC G1309Dfs*4 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-4791256] APC truncation mutants [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4791253] Rothfels, K, 2013-10-28
crossReference	[DatabaseIdentifier:12020752] Mondo:0005575 [DatabaseIdentifier:4791252] COSMIC:COSV57321812 [DatabaseIdentifier:4791249] COSMIC:COSV57321812
dbId	4791251
disease	[Disease:4791250] colorectal cancer
displayName	APC G1309Dfs*4 [cytosol]
endCoordinate	1311
hasModifiedResidue	[FragmentReplacedModification:4791248] Replacement of residues 1309 to 1311 by DWN
inDisease	true
literatureReference	[LiteratureReference:4791254] Mutations of the APC (adenomatous polyposis coli) gene
maxDepth	1
modified	[InstanceEdit:9967510] D'Eustachio, Peter, 2025-09-29
name	APC G1309Dfs*4 Adenomatous polyposis coli protein APC_HUMAN
referenceEntity	[ReferenceGeneProduct:uniprot:P25054] UniProt:P25054 APC
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-4791251
startCoordinate	2
updateTrackers	[UpdateTracker:9972288] Update Tracker - [EntityWithAccessionedSequence:4791251] APC G1309Dfs*4 [cytosol] - v95:[modifyStartCoordinate]

(updatedInstance)	[UpdateTracker:9972288] Update Tracker - [EntityWithAccessionedSequence:4791251] APC G1309Dfs*4 [cytosol] - v95:[modifyStartCoordinate]
(hasCandidate)	[CandidateSet:R-HSA-4791256] APC truncation mutants [cytosol]

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