Reactome | Phosphorylated TTP:mRNA Complex [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-450420] Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] - Danio rerio
consumedByEvent	[Reaction:R-DRE-450394] p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10587272
displayName	Phosphorylated TTP:mRNA Complex [cytosol]
hasComponent	[DefinedSet:R-DRE-450496-6] Homologues of p-S60,S186-ZFP36 [cytosol] [OtherEntity:R-ALL-450597] mRNA Transcript Targeted by Tristetraproline [cytosol] [EntityWithAccessionedSequence:R-DRE-180743] tnpo1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Homo sapiens
maxDepth	3
name	Phosphorylated TTP:mRNA Complex
producedByEvent	[Reaction:R-DRE-450463] MK2 phosphorylates ZFP36 (Tristetraproline, TTP) - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-450541
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-450394] p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta
(hasComponent)	[Complex:R-DRE-450420] Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol]
(output)	[Reaction:R-DRE-450463] MK2 phosphorylates ZFP36 (Tristetraproline, TTP)
(inferredTo)	[Complex:R-HSA-450541] Phosphorylated TTP:mRNA Complex [cytosol]

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