Reactome | GCK [cytosol]

Schema > EntityWithAccessionedSequence > Entries

GCK [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-170827] GCK1:GCKR complex [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex - Homo sapiens
created	[InstanceEdit:450085] D'Eustachio, P, 2009-12-11
dbId	450094
deleted	[Deleted:450109] Deletion of instance: 211355
displayName	GCK [cytosol]
endCoordinate	465
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-450094] GCK [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-450094] GCK [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-450094] GCK [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-450094] GCK [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-DRE-450094] gck [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-450094] gck [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-450094] GCK [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-450094] Hex-C [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-450094-2] GCK [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-450094-3] Hexl [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-450094-4] Hex-A [cytosol] - Drosophila melanogaster [DefinedSet:R-DME-450094-5] Homologues of GCK [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-450094] hxk-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-450094-2] hxk-3 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-450094-3] hxk-2 [cytosol] - Caenorhabditis elegans [DefinedSet:R-CEL-450094-4] Homologues of GCK [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-SPO-450094] GCK [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-450094-2] GCK [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-450094-3] Homologues of GCK [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-450094] GCK [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-450094-2] GCK [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-450094-3] GCK [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-450094-4] GCK [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-450094-5] GCK [cytosol] - Saccharomyces cerevisiae [DefinedSet:R-SCE-450094-6] Homologues of GCK [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-450094] GCK [cytosol] - Plasmodium falciparum
maxDepth	1
memberOf	[CandidateSet:R-HSA-450097] glucokinase and hexokinases [cytosol] - Homo sapiens
modified	[InstanceEdit:3222603] D'Eustachio, P, 2013-03-25
name	GCK glucokinase
producedByEvent	[BlackBoxEvent:R-HSA-9625124] GCK gene expression is inhibited by FOXO1, SIN3A and HDACs - Homo sapiens [Reaction:R-HSA-170799] cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) - Homo sapiens [BlackBoxEvent:R-HSA-170825] NPC exports GCK1 from nucleus - Homo sapiens [BlackBoxEvent:R-HSA-211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P35557] UniProt:P35557 GCK
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-450094
startCoordinate	1
updateTrackers	[UpdateTracker:9876709] Update Tracker - [EntityWithAccessionedSequence:450094] GCK [cytosol] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9876709] Update Tracker - [EntityWithAccessionedSequence:450094] GCK [cytosol] - v44:[modifyEndCoordinate]
(replacementInstances)	[Deleted:450109] Deletion of instance: 211355
(output)	[BlackBoxEvent:R-HSA-9625124] GCK gene expression is inhibited by FOXO1, SIN3A and HDACs [Reaction:R-HSA-170799] cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) [BlackBoxEvent:R-HSA-170825] NPC exports GCK1 from nucleus [BlackBoxEvent:R-HSA-211346] NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
(input)	[Reaction:R-HSA-170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
(hasComponent)	[Complex:R-HSA-170827] GCK1:GCKR complex [cytosol]
(hasMember)	[CandidateSet:R-HSA-450097] glucokinase and hexokinases [cytosol]

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