Reactome | CD4 binds Interleukin-16

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CD4 binds Interleukin-16 Show undefined attributes

authored	[InstanceEdit:5578882] Jupe, Steve, 2014-06-04
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:449066] Jupe, S, 2009-11-27
dbId	449087
displayName	CD4 binds Interleukin-16
edited	[InstanceEdit:8854731] Jupe, Steve, 2016-01-28
eventOf	[Pathway:R-HSA-449836] Other interleukin signaling - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-167542] CD4 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-447098] IL16(1212-1332) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:449085] The CD4-associated tyrosine kinase p56lck is required for lymphocyte chemoattractant factor-induced T lymphocyte migration [LiteratureReference:449086] Identification of a CD4 domain required for interleukin-16 binding and lymphocyte activation
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	CD4 binds Interleukin-16
orthologousEvent	[Reaction:R-XTR-449087] CD4 binds Interleukin-16 - Xenopus tropicalis [Reaction:R-SSC-449087] CD4 binds Interleukin-16 - Sus scrofa [Reaction:R-RNO-449087] CD4 binds Interleukin-16 - Rattus norvegicus [Reaction:R-MMU-449087] CD4 binds Interleukin-16 - Mus musculus
output	[Complex:R-HSA-449069] CD4:IL16(1212-1332) [plasma membrane]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-449087
summation	[Summation:449099] CD4 is a receptor for Interleukin-16 (IL16), explaining how ...

Referrals

(hasEvent)

[Pathway:R-HSA-449836] Other interleukin signaling

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