Reactome | CD4 binds Interleukin-16

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10480314
displayName	CD4 binds Interleukin-16
eventOf	[Pathway:R-SSC-449836] Other interleukin signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-449087] CD4 binds Interleukin-16 - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-167542] CD4 [plasma membrane] [EntityWithAccessionedSequence:R-SSC-447098] IL16 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	CD4 binds Interleukin-16
output	[Complex:R-SSC-449069] CD4:IL16(1212-1332) [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-449087
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-449836] Other interleukin signaling
(inferredTo)	[Reaction:R-HSA-449087] CD4 binds Interleukin-16

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