Reactome | IL24 binds to IL22RA1:JAK1:IL20RB

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IL24 binds to IL22RA1:JAK1:IL20RB Show undefined attributes

authored	[InstanceEdit:5578882] Jupe, Steve, 2014-06-04
category	uncertain
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:448729] Jupe, S, 2009-11-25
dbId	448708
displayName	IL24 binds to IL22RA1:JAK1:IL20RB
edited	[InstanceEdit:8854731] Jupe, Steve, 2016-01-28
eventOf	[Pathway:R-HSA-8854691] Interleukin-20 family signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8987012] IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 - Homo sapiens
input	[Complex:R-HSA-448727] IL22RA1:JAK1:IL20RB [plasma membrane] [EntityWithAccessionedSequence:R-HSA-448438] IL24 [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:448739] Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	IL24 binds to IL22RA1:JAK1:IL20RB IL20, IL24 bind to IL22RA1:JAK1:IL20RB receptor complex IL22RA:IL20RB is a receptor for IL20, IL24
orthologousEvent	[BlackBoxEvent:R-GGA-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Gallus gallus [BlackBoxEvent:R-SSC-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Sus scrofa [BlackBoxEvent:R-BTA-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Bos taurus [BlackBoxEvent:R-CFA-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Canis familiaris [BlackBoxEvent:R-RNO-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Rattus norvegicus [BlackBoxEvent:R-MMU-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Mus musculus
output	[Complex:R-HSA-448735] IL24:IL22RA1:JAK1:IL20RB [plasma membrane]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854753] Meldal, Birgit, 2016-01-28
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-448708
summation	[Summation:6804714] Interleukin-24 (IL24) (and Interleukin-20 (IL20)) can activa...
updateTrackers	[UpdateTracker:9780823] Update Tracker - [BlackBoxEvent:448708] IL24 binds to IL22RA1:JAK1:IL20RB - v62:[add_removeInput, modifyText] [UpdateTracker:9780894] Update Tracker - [BlackBoxEvent:448708] IL24 binds to IL22RA1:JAK1:IL20RB - v61:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780823] Update Tracker - [BlackBoxEvent:448708] IL24 binds to IL22RA1:JAK1:IL20RB - v62:[add_removeInput, modifyText] [UpdateTracker:9780894] Update Tracker - [BlackBoxEvent:448708] IL24 binds to IL22RA1:JAK1:IL20RB - v61:[modifyText]
(hasEvent)	[Pathway:R-HSA-8854691] Interleukin-20 family signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-8987012] IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1

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