Reactome | IL24 binds to IL22RA1:JAK1:IL20RB

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IL24 binds to IL22RA1:JAK1:IL20RB Show undefined attributes

category	omitted
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141194
displayName	IL24 binds to IL22RA1:JAK1:IL20RB
eventOf	[Pathway:R-RNO-8854691] Interleukin-20 family signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-8987012] IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 - Rattus norvegicus
inferredFrom	[BlackBoxEvent:R-HSA-448708] IL24 binds to IL22RA1:JAK1:IL20RB - Homo sapiens
input	[Complex:R-RNO-448727] IL22RA1:JAK1:IL20RB [plasma membrane] [EntityWithAccessionedSequence:R-RNO-448438] Il24 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IL24 binds to IL22RA1:JAK1:IL20RB IL20, IL24 bind to IL22RA1:JAK1:IL20RB receptor complex IL22RA:IL20RB is a receptor for IL20, IL24
output	[Complex:R-RNO-448735] IL24:IL22RA1:JAK1:IL20RB [plasma membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-448708
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8854691] Interleukin-20 family signaling
(precedingEvent)	[BlackBoxEvent:R-RNO-8987012] IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1
(inferredTo)	[BlackBoxEvent:R-HSA-448708] IL24 binds to IL22RA1:JAK1:IL20RB

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