Reactome | IL22 [extracellular region]

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IL22 [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-448738] IL22RA2:IL22 [extracellular region] - Homo sapiens [Complex:R-HSA-8987249] IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-448480] IL22 binds IL22RA1:JAK1 receptor complex - Homo sapiens [Reaction:R-HSA-448741] IL22RA2 binds IL22 - Homo sapiens
created	[InstanceEdit:448455] Jupe, S, 2009-11-24
dbId	448460
displayName	IL22 [extracellular region]
endCoordinate	179
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-448460] Il22 [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-448460] Il22 [extracellular region] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-448460] IL22 [extracellular region] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-448460] IL22 [extracellular region] - Bos taurus [EntityWithAccessionedSequence:R-SSC-448460] IL22 [extracellular region] - Sus scrofa [GenomeEncodedEntity:R-DRE-448460] Ghost homologue of IL22 [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-XTR-448460] IL22 [extracellular region] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-448460] IL22 [extracellular region] - Gallus gallus
maxDepth	1
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	IL22 Interleukin-22 IL22_HUMAN
positivelyRegulates	[PositiveRegulation:9850996] Positive regulation by 'IL22 [extracellular region]'
referenceEntity	[ReferenceGeneProduct:uniprot:Q9GZX6] UniProt:Q9GZX6 IL22
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-448460
startCoordinate	34

Referrals

(regulator)	[PositiveRegulation:9850996] Positive regulation by 'IL22 [extracellular region]'
(input)	[Reaction:R-HSA-448741] IL22RA2 binds IL22 [Reaction:R-HSA-448480] IL22 binds IL22RA1:JAK1 receptor complex
(hasComponent)	[Complex:R-HSA-448738] IL22RA2:IL22 [extracellular region] [Complex:R-HSA-448411] IL22:IL22RA1:JAK1 [plasma membrane] [Complex:R-HSA-8987249] IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane] [Complex:R-HSA-8987001] IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2 [plasma membrane]

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