Reactome | IL12B:IL23A [extracellular region]

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IL12B:IL23A [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor - Homo sapiens
created	[InstanceEdit:447133] Jupe, S, 2009-11-20
dbId	447217
displayName	IL12B:IL23A [extracellular region]
hasComponent	[EntityWithAccessionedSequence:R-HSA-447181] IL12B [extracellular region] [EntityWithAccessionedSequence:R-HSA-447245] IL23A [extracellular region]
inDisease	false
inferredTo	[Complex:R-MMU-447217] IL12B:IL23A [extracellular region] - Mus musculus [Complex:R-RNO-447217] IL12B:IL23A [extracellular region] - Rattus norvegicus [Complex:R-CFA-447217] IL12B:IL23A [extracellular region] - Canis familiaris [Complex:R-BTA-447217] IL12B:IL23A [extracellular region] - Bos taurus [Complex:R-SSC-447217] IL12B:IL23A [extracellular region] - Sus scrofa [Complex:R-XTR-447217] IL12B:IL23A [extracellular region] - Xenopus tropicalis [Complex:R-GGA-447217] IL12B:IL23A [extracellular region] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:8854642] The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12
maxDepth	2
modified	[InstanceEdit:8949841] Jupe, Steve, 2016-11-29
name	IL12B:IL23A Interleukin-12B:Interleukin-23A
producedByEvent	[BlackBoxEvent:R-HSA-8950741] IL12B:IL23A translocates from ER lumen to extracellular space - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-447217
updateTrackers	[UpdateTracker:9896536] Update Tracker - [Complex:447217] IL12B:IL23A [extracellular region] - v60:[addLiteratureReference, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9896536] Update Tracker - [Complex:447217] IL12B:IL23A [extracellular region] - v60:[addLiteratureReference, modifyName]
(output)	[BlackBoxEvent:R-HSA-8950741] IL12B:IL23A translocates from ER lumen to extracellular space
(input)	[BlackBoxEvent:R-HSA-447130] Interleukin-23 binds interleukin-23 receptor
(hasComponent)	[Complex:R-HSA-447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] [Complex:R-HSA-8950186] IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] [Complex:R-HSA-8950239] IL23A:IL12B:IL12RB1:p-TYK2:IL23R:p-JAK2 [plasma membrane]

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