Reactome | IL12B:IL23A [extracellular region]

Schema > Complex > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-RNO-447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[BlackBoxEvent:R-RNO-447130] Interleukin-23 binds interleukin-23 receptor - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10140951
displayName	IL12B:IL23A [extracellular region]
hasComponent	[EntityWithAccessionedSequence:R-RNO-447181] Il12b [extracellular region] [EntityWithAccessionedSequence:R-RNO-447245] Il23a [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-447217] IL12B:IL23A [extracellular region] - Homo sapiens
maxDepth	2
name	IL12B:IL23A
producedByEvent	[BlackBoxEvent:R-RNO-8950741] IL12B:IL23A translocates from ER lumen to extracellular space - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-447217
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-RNO-447130] Interleukin-23 binds interleukin-23 receptor
(output)	[BlackBoxEvent:R-RNO-8950741] IL12B:IL23A translocates from ER lumen to extracellular space
(hasComponent)	[Complex:R-RNO-447186] IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 [plasma membrane] [Complex:R-RNO-8950186] IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-447217] IL12B:IL23A [extracellular region]