Reactome | IRAK1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-193874] IRAK1:MYD88 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-446692] IRAK1 binds to MYD88 within the IL1R complex - Homo sapiens
created	[InstanceEdit:446650] Jupe, S, 2009-11-16
dbId	446639
displayName	IRAK1 [cytosol]
endCoordinate	712
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-446639] IRAK1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-446639] IRAK1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-446639] IRAK1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-446639] IRAK1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-446639] IRAK1 [cytosol] - Sus scrofa
maxDepth	1
memberOf	[DefinedSet:R-HSA-937023] IRAK1, IRAK2 [cytosol] - Homo sapiens
modified	[InstanceEdit:3448660] Wu, G, 2013-05-16
name	IRAK1 Interleukin-1 receptor-associated kinase 1 IRAK1_HUMAN
producedByEvent	[BlackBoxEvent:R-HSA-9615829] IRAK1 gene expression is inhibited by MECP2 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P51617] UniProt:P51617 IRAK1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-446639
startCoordinate	1
updateTrackers	[UpdateTracker:9876431] Update Tracker - [EntityWithAccessionedSequence:446639] IRAK1 [cytosol] - v44:[addEndCoordinate, addStartCoordinate]

(updatedInstance)	[UpdateTracker:9876431] Update Tracker - [EntityWithAccessionedSequence:446639] IRAK1 [cytosol] - v44:[addEndCoordinate, addStartCoordinate]
(output)	[BlackBoxEvent:R-HSA-9615829] IRAK1 gene expression is inhibited by MECP2
(hasComponent)	[Complex:R-HSA-193874] IRAK1:MYD88 [cytosol] [Complex:R-HSA-446693] IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:IRAK1 [plasma membrane] [Complex:R-HSA-8981951] IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane]
(input)	[Reaction:R-HSA-446692] IRAK1 binds to MYD88 within the IL1R complex
(hasMember)	[DefinedSet:R-HSA-937023] IRAK1, IRAK2 [cytosol]

Cite Us!