Reactome | IRAK1 gene expression is inhibited by MECP2

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9615665] Orlic-Milacic, Marija, 2018-08-07
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9615826] Orlic-Milacic, Marija, 2018-08-08
dbId	9615829
displayName	IRAK1 gene expression is inhibited by MECP2
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9615830] Irak1 gene expression is inhibited by Mecp2 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9615805] IRAK1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IRAK1 gene expression is inhibited by MECP2
output	[EntityWithAccessionedSequence:R-HSA-446639] IRAK1 [cytosol]
precedingEvent	[Reaction:R-HSA-9615801] MECP2 binds IRAK1 gene - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:9615827] Negative gene expression regulation by 'MECP2:IRAK1 gene [nucleoplasm]'
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9615829
summation	[Summation:9615836] Based on studies in mice, MECP2 represses IRAK1 gene transcr...

(hasEvent)	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
(inferredTo)	[BlackBoxEvent:R-MMU-9615830] Irak1 gene expression is inhibited by Mecp2

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