Reactome | Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL

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Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL Show undefined attributes

authored	[InstanceEdit:4419985] Jassal, B, 2013-08-29
catalystActivity	[CatalystActivity:4420005] phosphatase activity of pPPP phosphatase [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol [Compartment:5263266] cytoplasmic side of endoplasmic reticulum membrane
created	[InstanceEdit:4419985] Jassal, B, 2013-08-29
dbId	4419986
displayName	Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL
edited	[InstanceEdit:4419985] Jassal, B, 2013-08-29
eventOf	[Pathway:R-HSA-446199] Synthesis of dolichyl-phosphate - Homo sapiens
followingEvent	[Reaction:R-HSA-9937298] DHRSX oxidizes polyprenol to polyprenal - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-4419982] pPPP [cytoplasmic side of endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9937279] The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae [LiteratureReference:2028990] Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase [LiteratureReference:4420040] The ins(ide) and out(side) of dolichyl phosphate biosynthesis and recycling in the endoplasmic reticulum [LiteratureReference:4420004] Golgi-enriched membrane fractions from rat brain and liver contain long-chain polyisoprenyl pyrophosphate phosphatase activity
maxDepth	1
modified	[InstanceEdit:9937296] D'Eustachio, Peter, 2025-01-30
name	Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL
output	[SimpleEntity:R-ALL-111294] PPi [cytosol] [SimpleEntity:R-ALL-4419981] pPNOL [cytoplasmic side of endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-4419978] DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP - Homo sapiens
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4793945] D'Eustachio, P, 2013-10-29
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-4419986
summation	[Summation:4420025] In mammals, polyprenol pyrophosphate (pPPP) requires dephosp...
updateTrackers	[UpdateTracker:9939720] Update Tracker - [Reaction:4419986] Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL - v92:[modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9939720] Update Tracker - [Reaction:4419986] Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL - v92:[modifyText, removeLiteratureReference]
(hasEvent)	[Pathway:R-HSA-446199] Synthesis of dolichyl-phosphate
(precedingEvent)	[Reaction:R-HSA-9937298] DHRSX oxidizes polyprenol to polyprenal

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